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It works in conjunction with folate to help develop new cells and to support the function of existing cells (via a process called methylation)

The predicted inhibitor-binding mode of 1j with an orientation and conformation that favors most negative docking score when superimposed with the endogenous substrate NCA of the NNMT enzyme indicated that the analog binds consistent with the binding mode of NCA, i.e., the N1-atom of both ligands aligned almost identical, conferring similar molecular interactions with key residues within the active site of the enzyme

Social isolation affects the development of obesity and type 2 diabetes in mice (in Eng)

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