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Front Cell Infect Microbiol 10:572912 Rauch I, Deets KA, Ji DX et al (2017) NAIP-NLRC4 inflammasomes coordinate intestinal epithelial cell expulsion with eicosanoid and IL-18 release via activation of caspase-1 and -8

This uniqueness of HGF permits it to play a critical role, which engages paracrine positive feedback loops that prop up the growth and metastasis of cancer cells