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Mitochondria, unlike most organelles, are highlighted by their possession of two distinct membranes: an outer membrane (OMM) that encloses the organelle and interfaces with the cytosol, and an inner membrane (IMM) that displays morphological complexity

Cell Death Dis 10(11):822 Chen X et al (2021) Cellular degradation systems in ferroptosis

When alcohol is consumed in excess, the liver can become overwhelmed with its processing capacity

This adaptation allows them to tolerate massive oxidative loads that would trigger apoptosis in non-malignant cells, effectively creating a privileged redox state that immune cells lack