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6 Division of Pulmonary and Critical Care Medicine, Department of Medicine, UCSF, San Francisco, California, USA

Always consult a licensed healthcare provider before beginning any new injection, infusion or supplement program, especially if you have underlying health conditions or take prescription medications

Although these elements might support the autoinflammatory nature of AS, studies demonstrating the presence of autoantibodies (such as anti-CD74, anti-sclerostin and anti-noggin antibodies) and evidence of activation and clonal expansion of T cell populations support an autoimmune component to the disease

At week 24, higher proportions of adolescents from the ritlecitinib treatment groups (30mg) had SALT scores 20 (17%28%) and 10 (6%28%) vs placebo and 10mg groups (0%)