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Authors thank for financially supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education (NRF-2020R1I1A2066868), the National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIT) (No

Exposure of recombinant CD38 + cells to isatuximab produced near-complete inhibition of the CD38 cyclase activity in a dose-dependent manner, while both a surrogate antibody for daratumumab (produced based on published sequences and thus potentially not completely identical to the original antibody) and daratumumab resulted in a much lower inhibition [19, 21, 22]