5 amino 1mq dose injection 5-Amino-1MQ (5mg & 50mg) for Research Pura Research Peptides | High-Purity

5-Amino-1MQ (5-Amino-1-methylquinolinium iodide, CAS 42464-96-0) is a synthetic small-molecule quaternary quinolinium compound that functions as a selective substrate site-targeting inhibitor of nicotinamide N-methyltransferase (NNMT)

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Unlike peptides, 5-Amino-1MQ is not synthesized by solid-phase peptide synthesis

The first cardiovascular study of NNMT enzyme inhibition in a heart failure with preserved ejection fraction (HFpEF) mouse model demonstrated that treatment markedly reduced 1-MNA (by 77.1%), 2PY (by 66.2%), and 4PY (by 71.1%) in cardiac tissue, while improving cardiac function, enhancing global longitudinal strain, reversing peak longitudinal strain rate, and significantly reducing left ventricular hypertrophy and fibrosis