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It primarily manifests in the intima of affected arteries as lipid depositions, infiltrations of monocytes and lymphocytes, the migration and proliferation of vascular smooth muscle cells (VSMCs), and the formation of foam cells, lipid striations, and fibrous plaques, which further contributes to vascular wall sclerosis, stenosis, and thrombosis

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30 Radiculopathies can not only produce significant weakness, numbness, dysesthesia and radicular pain, but can also cause unilateral or bilateral proximal or distal muscle cramps in the affected myotome

Oral treatment with Lactobacillus rhamnosus attenuates behavioural deficits and immune changes in chronic social stress