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Therefore, this paper strongly recommends that the Ethiopian government develop and enforce regulations on these environmental issues and implement intervention measures at the kebele level

Furthermore, homocysteine-induced apoptosis is mainly mediated by induction DNA injury and energy depletion (Fan et al

It is noteworthy that two Arg residues, Arg140 and Arg172, are thought to be crucial for IDH2 activity because their frequent mutations have been observed in several cancer-associated diseases 4, 5

However, GLS2 exhibits tumor heterogeneity and is found to be upregulated in specific malignancies, such as breast cancer, thereby promoting oncogenesis (37)