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Return and Re-Use of Released Glutamate It is well established that virtually all released transmitter glutamate is accumulated specifically into astrocytes by the two transporters GLAST (EAAT1) and Glt1 (EAAT2) (Danbolt, 2013) is reproduced in Figure 6 and shows that oxidation of glutamate can supply energy supporting not only the increased demand created by its own uptake (e.g., McKenna, in vitro and partly to the late turns of the TCA cycle during which some the labeled atoms are oxidized

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