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doi: 10.1038/nature17184

This is the application area with the deepest preclinical history, and it is also where oral administration has a particularly direct anatomical rationale - the compound passes through the GI tract it was originally studied in relation to

By utilizing indigenous knowledge and the bioactive compounds found in medicinal plants, TM can offer potential solutions to unmet treatment needs, improve healthcare accessibility, and promote holistic approaches to IBD management in African populations [74]

By using this method, we produced a GPx3 mutant, which showed significant activity in reducing both H 2 O 2 and PLPC-OOH