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A small percentage of it is converted by phase I cytochrome P450 (CYP) enzymes to a chemically reactive metabolite (N-acetyl-p-benzoquinone imine, NAPQI), which can be detoxified by directly binding with glutathione (GSH) or by GSH-s-transferases (GST) [4]

developed a mucosal interface biomedical device inspired by the multilayered villous topography of the small intestine, known as the Intra-Mathematical Bioengineering MNs (IMBEMs) (Fig

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