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However, under reductive stress, protein disulfide bonds inappropriately form, resulting in activation of the unfolded protein response and ER stress (60)

84 Multiple controlled trials have shown NAC can improve the effectiveness of ovulation-inducing medications in women with infertility due to PCOS

It is downregulated in gastric and colorectal cancers but upregulated in lung adenocarcinoma and breast tumors compared to normal tissue (Liu et al., 2017

Accordingly, the disadvantage of these models is the absence of a simple way to assess barrier function such as TEER measurement and complicated permeability screening (Cho et al., 2017)