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1 Introduction Radiotherapy, a pivotal treatment modality for cancer, is employed in more than 50% of the cases in curative and palliative care ( While most current research focuses on the care of acute radiation dermatitis, there remains a significant unmet need for more effective interventions targeting the prevention and treatment of chronic radiation-induced skin fibrosis

Her result at the six-month mark scored a clinically meaningful improvement on the Global Aesthetic Improvement Scale (GAIS), and her self-reported satisfaction was nine out of ten

The dermis was then carefully separated from the full-thickness skin specimens and soaked in collagenase solution (collagenase C7657 Sigma, 2 mgmL 1 ) at 37 C for 1 h with gentle agitation

6g,h), indicating the rescue effects of erucamide in rd10 mice are mediated by erucamideTMEM19 through the downstream angiogenic and neurotrophic factors of VEGFa, FGF-2 and TNF