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[DOI] [PMC free article] [PubMed] [Google Scholar] 46.Klimberg VS, Souba WW, Dolson DJ, Salloum RM, Hautamaki RD, Plumley DA, et al

According to the latest report by the International Diabetes Federation (IDF) ( The pathogenesis of DCM is exceptionally complex, involving dysregulation of glucose and lipid metabolism, insulin resistance, oxidative stress, inflammatory responses, mitochondrial dysfunction, and ferroptosis ( Ferroptosis is a form of programmed cell death induced by iron-mediated lipid peroxidation ( This review will focus on exploring the role of ferroptosis and mitochondrial injury in cardiac cells exposed to chronic diabetic conditions, their impact on patients with diabetes, and the associated pathophysiological mechanisms

Research has shown that glutathione supplementation can improve liver enzyme markers, bilirubin levels, and protein levels in people with fatty liver disease. This isnt a fringe finding its one of the most well-documented applications of glutathione in clinical research

In addition, PTER is less susceptible to phase II liver metabolism (Zhou et al., 2016)