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Oral intake of vitamin B12 has a complex absorption mechanism involving "intrinsic factor", and typically only 1% of oral vitamin B12 is absorbed, so it is interesting that the levels used in this study were sufficient to substantially improve methylation, glutathione, and oxidative stress

Because absorption is the problem, management is directed by a provider and commonly bypasses the gut

for example, the predictions of the organic carbon content of soil (%) are not 1:1 with the predictions of soil organic carbon density (kg m 3 ), which is also illustrated in Figs

This keeps the work aligned with regulatory guidance while still allowing for detailed exploration of how the peptide behaves in various models