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Figure 1 shows the selection process based on the PRISMA flow chart of the studies analyzed in this manuscript

112]**PEER REVIEWED** Specific heat of liquid: 2.6 J/g (0.62 cal/g) at 20 deg C

The Warrants are subject to an acceleration clause should the Common Shares have a closing price on the Canadian Securities Exchange (or such other exchange on which the Common Shares may be traded at such time) of CAD $3.00 or greater per Common Share for a period of five (5) consecutive trading days at any time that is four months and one day from the closing date, in which event the Company may notify warrantholders that the Warrants must be exercised within a period of 30 days, or they will expire