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Recent study shows that overactivation of MYC detected in ALS astrocytes induce alterations in EV release and these alterations trigger astrocyte-to-neuron miscommunication, resulting in reduced support of neighboring neurons (Fioretti et al., 2025)

Nigral iron levels were significantly elevated in both PD patients and MPTP-intoxicated macaques consistent with previous reports, using MRI 12,13,14,32,33,34,35 or histology 10,36,37,38,39,40

Ever since B12 emerged in the 60s, when it was often mixed with amphetamines, and then later, when everyone from Madonna to Margaret Thatcher was trying it out, its efficacy has been the subject of debate

10.1136/bcr-2017-220928 256