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Using isotope tracers, the authors showed that, in BAT, cold exposure increases glucose and lipid uptake, accompanied by an increase in oxidative activity

Hamowanie tego etapu podnosi w modelach pul nikotynamidu dostpn do regeneracji NAD (przez szlak ratunkowy) oraz oszczdza S-adenozylometionin, ograniczajc jej drena na reakcje metylacji nikotynamidu