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Some of the signs and symptoms of this deficiency can include anemia, the buildup of too much acid in the body (metabolic acidosis), frequent infections and symptoms caused by problems in the brain (including seizures, intellectual disability and loss of coordination)

10.3389/fphar.2021.712876 22 LiuJ.DuJ.LiY.WangF.SongD.LinJ.et al (2022)

We designed an antagonist peptide of VEGF-A and VEGF-B reproducing two discontinuous receptor binding regions of VEGF-B (loop 1 and loop3) covalently linked together by a receptor binding region of VEGF-A (loop3)

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