This suggests a case of parallel adaptation to dietary extremes through distinct, population-specific genetic changes: the ancestral allele, combined with the insertion, helps vegetarians better metabolize their diet, while the derived allele is best suited for marine diets ( The FADS2 insertion allele in South Asians is believed to be an adaptive response to plant-based diets that provides a metabolic advantage by ensuring sufficient AA and DHA synthesis from vegetarian food sources ( FADS alleles common in Inuit reduce levels of certain unsaturated fatty acids, which was likely beneficial in their ecology, where they consumed large amounts of seal, blubber, and fish oil daily
J Neurochem 71:25102517 Rossato MS, Brilli E, Ferri N, Giordano G, Tarantino G (2021) Observational study on the benefit of a nutritional supplement, supporting immune function and energy metabolism, on chronic fatigue associated with the SARS-COV-2 post-infection progress
Supplementing with L-CARNITINE improves both sprint and endurance performance
In mammals, CAC can accept acylcarnitines with acyl chains of various lengths from 2 to 18 carbon atoms as substrates, but it showed a higher affinity for acylcarnitines with longer carbon chains (Indiveri et al., 2011)
