With Glutathione as its main ingredient, it inhibits the production of melanin in the skin, which naturally lightens and brightens your skin complexion
The higher temperatures and greater sunlight exposure may have resulted in excess ROS production at the beginning of the study period in September, then decreased over time with the temperature and sunlight declines in October and November
The following serious adverse reactions are discussed elsewhere in the labeling: Hepatic Injury [see Warnings and Precautions (5.1)] Serious Skin Reactions [seeWarnings and Precautions (5.2)] Allergy and Hypersensitivity [see Warnings and Precautions (5.4)] Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed cannot be directly compared to rates in other clinical trials and may not reflect the rates observed in practice
In parallel, microarray data generated by Steiner et al., who isolated mantle cells after having used copper to lesion hair cells, showed a complicated damage response consisting of upregulation of a subset of the Wnt pathway components and target genes ( Wnt3 , Wnt7a , Wnt9a ) but downregulation of others ( Wnt9a , Axin2 , Tcf4 , Sfrp2 ) immediately after damage (Steiner et al., 2014)
