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Euthyroid Adaptation and Subclinical Risk While LT4-treated hypothyroid patients are especially sensitive to these changes, even euthyroid individuals may experience functional adaptation to a KD that mirrors elements of low T3 syndrome

The in vivo titer of conjugated Dex was about 50 times that of nonconjugated Dex

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In summary, our data demonstrate that increased radioresistance of cancer cells expressing the clinically relevant activation-associated AKT mutant protein AKT-E17K involves multiple metabolic mechanisms: On the one hand, AKT-E17K promoted increased glycolytic activity at basal state and improved the capability of the cells for activating compensatory glycolysis upon irradiation