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Taken together, we expected that chronic exposure to DEHP at environmentally relevant doses would not be toxic, but would rather modulate cDC differentiation, which in turn would modify the magnitude of the resultant allergic response

Because RA is immune-driven, it tends to strike both sides of the body symmetrically and can also affect organs beyond the joints

Moreover, MZB entry and retention in the splenic marginal zone are tightly regulated by chemotactic molecules, such as C-X-C Motif Chemokine Ligand 13 (CXCL13) and sphingsoine-1-phosphate (S1P) 54