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liposomes caused by varying sizes or labeling efficiency (Maas et al., 2015)

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Ong F, Garcia-Manero G, Montalban-Bravo G, Alvarado Y, Ohanian M, Konopleva M, Jabbour E, Jain N, Borthakur G, DiNardo CD, Daver N, Issa GC, Sasaki K, Chien KS, Takahashi K, Andreeff M , Muftuoglu M, Delumpa R, Mayor E, Loiselle C, Waller L, Banks G, Kantarjian H, Cortes JE, and Short N

Thus, topically applied formulations may target different skin compartments, such as the viable epidermis, known as the key target region for the majority of topical products [85]