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10.1016/s0140-6736(88)92354-9 Lancet

Moura IC, Centelles MN, Arcos-Fajardo M, Malheiros DM, Collawn JF, Cooper MD, et al

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Although CHAC1 mRNA levels remain elevated, the lack of methionine, essential for initiating protein synthesis, prevents the translation of CHAC1 mRNA into functional protein