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doi: 10.3389/fnagi.2021.667032 39

Combined B 12 and iron deficiency Iron deficiency is a condition that could lead to masking of megaloblastic anemia caused by vitamin B 12 and folate deficiencies (Remacha et al., 2013)

Indeed, this class is absent in cyanobacteria and a single gene, that likely represents the ancestor DHAR gene, is found in a few algae of the chlorophyceae and trebouxiophyceae classes but not in prasinophyceae