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Chronic hyperglycemia may also impair astrocytic regulation of blood flow [50]

Individual response varies considerably, with some participants experiencing meaningful fat loss while others showed minimal changes

GLP-1 receptor agonists like semaglutide (Ozempic/Wegovy) and the dual GLP-1/GIP drug tirzepatide (Mounjaro/Zepbound) work by mimicking gut hormones that slow digestion, blunt appetite, and improve how your body handles blood sugar