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Short-chain fatty acids modify colonic motility through nerves and polypeptide YY release in the rat

9 Summary The available literature indicates that non-medical use of exogenous testosterone and other anabolicandrogenic steroids (AAS) is associated with a broad spectrum of multisystem adverse effects mediated by oxidative stress, mitochondrial dysfunction, endocrine disruption, and epigenetic mechanisms

And in patients with diabetes mellitus, there was a 41% reduction in clinical events, including a 43% reduction in deaths over 5 years