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Description

Furthermore, transgenic Drosophila models expressing human AD-associated genes, such as amyloid-beta (A) and tau, have enabled precise exploration of disease progression and therapeutic interventions (Table 13)

The antioxidant enzymes glutathioneperoxidase, catalase, and superoxide dismutase (SOD) metabolize oxidative toxic intermediates

For example, the metabolism of nitroglycerin requires interaction with thiols such as cysteine and GSH for transformation to vasoactive metabolites such as nitrosothiols or nitric oxide