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This leads to a reduction in ovarian reserve and a higher occurrence of chromosomal abnormalities especially aneuploidy in oocytes 3,4 , increasing the risks of infertility, pregnancy loss, perinatal mortality, and congenital disorders in women at an advanced age 5,6

A healthy gut lining is the first line of defense for the immune system

An elevated level of EAA is a significant risk factor for severe sepsis and is associated with increased organ dysfunction and mortality [390]

This can lead to copper sequestration in misfolded fibrils along with copper deficiency in the mitochondria, causing impaired energy production (Min et al., 2024)