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arguments against the use of oral cobalamin Oral treatment may be considered in certain situationsfor example, in mild or subclinical deficiency with no clinical features and when absorption and compliance are definitely not a problem

They cannot by themselves establish: A safe human amount A safe route of administration Long-term human safety Interaction risks Reproductive or developmental safety Clinical effectiveness Which individuals, if any, might be suitable for an authorised use The number of animal papers should not be presented as equivalent to a programme of large, well-controlled human clinical trials

Peptides do not cause accidents

Archivos de Medicina , 18 (2), 4