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Furthermore, the original co-crystallized ligand inside the active site may affect the conformation of the protein and, as a consequence, the binding mode of other ligands

The dendritic cells show enhanced phenotypic and functional maturation and produce a considerable amount of IL-10 and IL-12 due to the presence of lentinan (115)

The clinical evidence for the diverse strategies discussed above, ranging from direct antioxidants to multi-targeted agents, is summarized in Table 1, which illustrates the varied outcomes and highlights the ongoing translational challenges

[DOI] [PMC free article] [PubMed] [Google Scholar] 14.Abrams MB, Nilsson I, Lewandowski SA, Kjell J, Codeluppi S, Olson L, et al