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Loeser and Ward demonstrated that experimental deafferentiation of neurons in the spinal cord of cat (by dorsal rhizotomy or hemicordotomy) results in spontaneous hyperactivity and abnormal firing of second-order neurons [ 149 ]

1 Introduction Epidemiological evidence suggests a close association between air pollution, resulting from the increased use of liquid petroleum, coal, and gas in transportation, industry, and domestic settings, and pulmonary mortality and morbidity

10.1007/s11357-019-00052-8 Geroscience 37 DongY.SameniS.DigmanM