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While animal studies show a good safety profile, a theoretical risk involving its pro-angiogenic effects and potential cancer promotion is a point of consideration, though no evidence has supported this risk in practice

These anti-apoptotic and pro-apoptotic molecules respectively showed no differences amongst the exercise and sedentary groups despite it being postulated that the reduction in renal tissue cell death in the exercise group could be due to the increase in anti-apoptotic molecule Bcl2 compared with BAX

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In the future, the identification of specific genes or pathways could serve as direct targets, in conjunction with cysteine deprivation for cancer therapy