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All TARDBP family fibroblasts, apart from the late-stage patient fibroblasts, had a higher expression level of OPA1 than unrelated controls, while MFF content was slightly higher only in TDP-43 G376D Asymptomatic and late-stage patient fibroblasts compared to both unrelated and familial CTRLs (Fig

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The strongest, best-documented effects are the antioxidant support and the gradual evening of skin tone

solvent not reported) is capable of enhancing mitochondrial activity while acting against oxidative stress and improving mitochondrial membrane potential (Bej et al., 2024b)