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A recent bioinformatic study that comparatively analyzed nine retinal proteomes and classified them on the basis of their specificity of gene expression and tissue distribution reported that proteins expressed in the retina exhibited increased propensity for phase separation due to elevated intrinsic protein disorder whereas broadly expressed proteins in multiple tissues were more ordered with higher structural stability (97)

10.1016/j.intimp.2021.108159 [DOI] [PubMed] [Google Scholar] Wang Q., Ou Y., Hu G., Wen C., Yue S., Chen C., et al

While topical hyaluronic acid is considered safe, oral supplements require more caution