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Taking vitamin B 12 supplements affects the genes expressed by bacteria living on our skin, report researchers at the University of California, Los Angeles (UCLA) in Science Translational Medicine [1] on 24 June 2015

They asked which one and was it first or second and had I had reaction to first one

Fernandez-Mendoza J, Vgontzas AN, Calhoun SL, et al

Inflammatory responses and metabolic disorders in the tumor microenvironment suppress immune cell activity.The product inhibits NNMT, reduces inflammatory factor levels, improves the tumor microenvironment, promotes immune cell infiltration and activation, and thereby enhances the recognition and killing of tumor cells by immunotherapeutic agents, offering a new strategy for cancer immune combination therapy