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applanatum presented antitumor activity against carcinoma cell lines (Osiska -Jaroszuk et al., 2014)

Chen et al (93) demonstrated that PGAM5, a mitochondrial phosphatase, dephosphorylates the Ser13 residue of FUNDC1, resulting in an increased association with LC3 during hypoxia or after treatment with a mitochondrial oxidative phosphorylation uncoupler (FCCP)

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One unique feature of 4Fe4S is that it can be cleaved to either one 3Fe4S cluster or two 2Fe2S clusters