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Description

IL-36 signaling amplifies Th1 responses by enhancing proliferation and Th1 polarization of naive CD4+ T cells

Functionally, patient specific PFIC1 hiHeps exported less BA than healthy hiHeps and hAH hepatocytes (basal FXR activity: hiHeps control: 0.960.06, PFIC1 hiHeps #1: 0.090.05 and hAH: 1.370.15)