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A double-blind, placebo-controlled trial in 90 HIV-positive patients with symptomatic distal symmetrical polyneuropathy found no benefit of intramuscular injection with 1 g/day of ALCAR for two weeks in the intention-to-treat analysis, but there was some pain relief in the group of 66 patients who completed the trial (84)

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[DOI] [PubMed] [Google Scholar] 27.Diaz Vivancos P., Wolff T., Markovic J., Pallardo F.V., Foyer C.H

Although the precise mechanisms of action of Delta Sleep-Inducing Peptide (DSIP) are not fully understood, research suggests that DSIP peptide modulates multiple neurotransmitter systems, including glutamate, GABA, and serotonin