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Rescue Activity of Fer-1 Analogs (Dixon, et al., 2012) HT-1080 cells are cultured in DMEM containing 10% fetal bovine serum, 1% supplemented non-essential amino acids and 1% pen/strep mixture (Gibco) and maintained in a humidified environment at 37 C

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Next, to analyze a possible beneficial role for ENDO3 against eTLR-mediated inflammation in vivo, we used a well-established model of CpG-ODN-induced systemic inflammation in mice 31