glutathione in borrelia

glutathione in borrelia Novel Diagnosis of Lyme Disease: Potential for CAM Intervention Frontiers | Tick HRF-dependent ferroptosis

Name: glutathione in borrelia Novel Diagnosis of Lyme Disease: Potential for CAM Intervention Frontiers | Tick HRF-dependent ferroptosis
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Frontiers Tick HRF dependent ferroptosis pathway to promote tick acquisition of Babesia microti Role of glutathione metabolism in host defense against Borrelia burgdorferi infection PNAS Borrelia burgdorferi infection modifies protein content in saliva of Ixodes scapularis nymphs BMC Genomics Springer Nature Link The peptidoglycan of Borrelia burgdorferi can persist in discrete tissues and cause systemic responses consistent with chronic illness Science Translational Medicine

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Our findings could promote the development of more efficient treatments, for example, combined treatment, including chemoradiotherapy, glucose control, and mitochondrial dysfunction

Deficiency of sirtuin 3 (SIRT3), a mitochondrial NAD+-dependent deacetylase, can lead to excessive acetylation of renal tubular mitochondrial proteins, inhibit the LKB1-AMPK signaling pathway, disrupt fatty acid metabolism, and cause mitochondrial dysfunction, which is an important mechanism underlying the development of RF [82, 83]