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TRG sensitized chemo-resistant head and neck cancer (HNC) cells to in vitro and in vivo RSL3 treatment by decreasing the activity of the Nrf2-ARE pathway ( in vitro and in vivo by the inhibition of the Nrf2-ARE pathway ( Sanguinarine (SAG) is a natural benzophenanthridine alkaloid from Sanguinaria Canadensis L

Lactobacillus and Bifidobacterium strains have been reported to enhance antioxidant capacity and reduce inflammation in animal models of sepsis (Takeaki, 2025)

Mishra N, Jiang C, Chen L, Paul A, Chatterjee A, Shen G (2023) Achieving abiotic stress tolerance in plants through antioxidative defense mechanisms

Methods : 3,5-Diethoxycarbonyl-1,4-dihydrocollidine (DDC), a xenobiotic compound that causes accumulation of porphyrin plugs in bile ducts, was fed to Glul fl/fl mice subjected to global Wnt inhibition using a PORCN inhibitor that blocks secretion of Wnt ligands, AAV8-Cre-mediated recombination to delete hepatic GS, or both