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Notably, the ZFPG + US group demonstrated the strongest cytotoxicity among all these groups, indicating a synergistic anti-tumor effect resulting from ZFPG-mediated enzyme dynamic therapy (EDT) and sonodynamic therapy (SDT)

At the molecular level, it modulates the expression of over 4,000 human genes, roughly 6% of the genome, according to a 2012 Broad Institute Connectivity Map analysis published by Pickart, Campbell, and colleagues

We would like to thank the beamline staff on I02 at Diamond Light Source and Proxima1 at SOLEIL

73 While glucagon-like peptide-1 receptor (GLP-1R) and glucagon receptor (GCGR) are emerging as the famous B1 GPCR targets in regulating blood glucose homeostasis and lipid metabolism