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Description

VPS35 gene mutations can lead to mitochondrial dysfunction and autophagy defects, preventing the timely clearance of aggregated proteins and thereby promoting Lewy body formation, followed by damage to dopaminergic (DA) neurons [18]

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Bradbury et al., 1972

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Symptoms typically begin 310 hours after the last drink and peak the following morning

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The association of TMB/MSI with IGF-1/IGF-1R expression was evaluated

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