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Hypoglycemia can be both physiological (occurring during fasting and heavy physical exertion) and pathological (accompanying a number of diseases, such as diabetes mellitus)

Margriet S, Westerterp-Plantenga MPGML, Eva MR, Kovacs (2005) Body weight loss and weight maintenance in relation to habitual caffeine intake and green tea supplementation

On the other hand, the combination of iron deficiency and chronic unpredictable mild stress (CUMS) can induce depressive episodes in mice and exacerbate depressive symptoms

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