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Abstract Traumatic brain injury (TBI) is a major global health concern and is increasingly recognized as a risk factor for neurodegenerative diseases including Alzheimers disease (AD) and chronic traumatic encephalopathy (CTE)

Side Effects While generally well-tolerated, Oral Estradiol can be associated with side effects

Saudi J Biol Sci 17(4):269274 Wang X, Huang S, Liu Y, Li D, Dang Y, Yang L (2021) Effects of ketogenic diet on cognitive function in pentylenetetrazol-kindled rats

In hepatocellular carcinoma cells, melatonin increases ROS accumulation and promotes apoptosis by inhibiting GSH levels (Ordoez et al., 2015)