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Their descendants carried the mutation, making the trait more common in the area

For example, vitamins and minerals are required co-factors for the production of many neurotransmitters and their pre-cursors, so vitamin/mineral supplementation may have also affected neurotransmitter status, and that may have contributed to improvements in autism severity and overall symptoms

Research has indicated that when iron ions are present at specific concentrations, they can inhibit the activity of Runt-related transcription factor 2 (Runx2), a critical regulator of osteoblast differentiation ( Figure 2 )

Pericytes of the neurovascular unit: key functions and signaling pathways