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These results reveal a link between the hexosamine pathway derived from the fructose-6-phosphate of the glycolytic pathway and innate antiviral immunity

J Clin Investig 132:e156243e156253 Evans-Molina C, Sims EK, DiMeglio LA, Ismail HM, Steck AK, Palmer JP, Krischer JP, Geyer S, Xu P, Sosenko JM (2018) Cell dysfunction exists more than 5 years before type 1 diabetes diagnosis