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Homocysteine metabolism gene polymorphisms (MTHFR C677T, MTHFR A1298C, MTR A2756G and MTRR A66G) jointly elevate the risk of folate deficiency

(Hong et al., 2015)

This study showed that SREBP1a, a major isoform in immune cells, links lipid metabolism to the innate immune response by activating lipogenesis and inflammasome formation